Products 1139889-93-2

CAS 1139889-93-2 appears in our catalog under these names: Golgicide A, Golgicide A/ 99.93% (existing batch purity), Golgicide A 99%, Golgicide A 1PC X 10MG, Golgicide A, 99%, 99%. Offered by: TRC, TargetMol, Biosynth, Ambeed, Sigma-Aldrich. Available pack sizes: 100mg, 5mg, 10mg, 25mg, 50mg, 500mg, 1mg, 10 mg.

Golgicide A
TRC, Biosynth
  • size: 100mg, 1mg, 5mg, 10mg
  • Variants: 4
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Golgicide A/ 99.93% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 558.88
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Golgicide A 99%
Ambeed
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 426.00
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Golgicide A 1PC X 10MG
Sigma-Aldrich
  • size: 10MG
  • Variants: 1
from 443.00
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Golgicide A, 99%, 99%
Chemat
  • size: 5mg, 25mg, 50mg, 1mg
  • Variants: 5
from 98.00
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Golgicide A, 99.94%
MedChemExpress
  • size: 10 mg, 5 mg, 100 mg, 50 mg
  • Variants: 6
from 463.66
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Golgicide A
GLPBio
  • size: 10mg, 25mg, 5mg
  • Variants: 3
from 690.65
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Structural formula: {0} (CAS {1})

Golgicide A is a diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181). It has a role as a cis-Golgi ArfGEF GBF inhibitor. It contains a cis-golgicide A and a trans-golgicide A.

Source: ChEBI

Identity
Molecular formulaC17H14F2N2
Molecular weight284.30 g/mol
IUPAC name(3aR,9bS)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
InChIKeyNJZHEQOUHLZCOX-FTLRAWMYSA-N
SMILESC1C=C[C@H]2[C@@H]1C(NC3=C2C=C(C=C3F)F)C4=CN=CC=C4

Computed by PubChem (NCBI)

Synonyms: Golgicide A, 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline, Golgicide A?, Golgicide A; GCA, Golgicide A (GCA), orb1300701, Golgicide A, >=98% (HPLC)