Products 1613724-42-7
CAS 1613724-42-7 appears in our catalog under these names: HTH-01-015/ 98.38% (existing batch purity), HTH–01–015, HTH-01-015 98%, 4,5,13-Trimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one, 98%, 98%, HTH-01-015, 98.81%. Offered by: TargetMol, GLPBio, Ambeed, Chemat, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).
HTH-01-015 is an organic heterotetracyclic compound that is 5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one substituted by methyl groups at positions 4, 5 and 13, and by a [1-(piperidin-4-yl)-1H-pyrazol-4-yl]amino group at position 2. It is a potent NUAK1 inhibitor (IC50 = 100 nM). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of piperidines, a member of pyrazoles, an aromatic amine, an organic heterotetracyclic compound, a secondary amino compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C26H28N8O |
|---|---|
| Molecular weight | 468.6 g/mol |
| IUPAC name | 2,7,9-trimethyl-5-[(1-piperidin-4-ylpyrazol-4-yl)amino]-2,4,6,9-tetrazatetracyclo[9.8.0.03,8.013,18]nonadeca-1(19),3,5,7,11,13,15,17-octaen-10-one |
| InChIKey | CHSDJDLAKKAWCI-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=NC(=N1)NC3=CN(N=C3)C4CCNCC4)N(C5=CC6=CC=CC=C6C=C5C(=O)N2C)C |
Computed by PubChem (NCBI)