Irinotecan (hydrochloride trihydrate) (Standard)
cas: 136572-09-3 — see every product listed under this CAS number, including other names
Irinotecan (hydrochloride trihydrate) (Standard) (CAS 136572-09-3) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 100 mg, 50 mg, 25 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-16568R-5 mg |
| cas | 136572-09-3 |
| size | 5 mg |
| availability | Get quote |
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 5 mg | 361.49 Pln | |
| MedChemExpress | 100 mg | 1545.71 Pln | |
| MedChemExpress | 50 mg | 1072.02 Pln | |
| MedChemExpress | 25 mg | 751.58 Pln | |
| MedChemExpress | 10 mg | 477.59 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Irinotecan hydrochloride hydrate is a hydrate that is the trihydrate form of irinotecan hydrochloride. Onivyde is used in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an antineoplastic agent, a prodrug, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. It contains an irinotecan hydrochloride (anhydrous).
Source: ChEBI
| Molecular formula | C33H45ClN4O9 |
|---|---|
| Molecular weight | 677.2 g/mol |
| IUPAC name | [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;trihydrate;hydrochloride |
| InChIKey | KLEAIHJJLUAXIQ-JDRGBKBRSA-N |
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl |
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