Irinotecan (hydrochloride) (Standard)
cas: 100286-90-6 — see every product listed under this CAS number, including other names
Irinotecan (hydrochloride) (Standard) (CAS 100286-90-6) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 100 mg, 5 mg, 10 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-16562AR-25 mg |
| cas | 100286-90-6 |
| size | 25 mg |
| availability | Get quote |
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 751.58 Pln | |
| MedChemExpress | 100 mg | 1545.71 Pln | |
| MedChemExpress | 5 mg | 361.49 Pln | |
| MedChemExpress | 10 mg | 477.59 Pln | |
| MedChemExpress | 50 mg | 1072.02 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Irinotecan hydrochloride (anhydrous) is a hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an antineoplastic agent, a prodrug, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. It contains an irinotecan(1+).
Source: ChEBI
| Molecular formula | C33H39ClN4O6 |
|---|---|
| Molecular weight | 623.1 g/mol |
| IUPAC name | [(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride |
| InChIKey | GURKHSYORGJETM-WAQYZQTGSA-N |
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl |
Computed by PubChem (NCBI)
Synonyms:
Irinotecan hydrochloride, Campto, Camptothecin 11 hydrochloride, Irinotecan hydrochloride anhydrous, 7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxy camptothecin hydrochloride, irinotecan hydrochloride (anhydrous), Irinomedac, Irinotecan hydrochloide, Irinotecan Hydrochloride 40 mg/2 mL, Irinotecan Hydrochloride 100 mg/5 mL