Irinotecan hydrochloride anhydrous

cas: 100286-90-6 — see every product listed under this CAS number, including other names

Irinotecan hydrochloride anhydrous (CAS 100286-90-6) is a chemical reagent available from Chemat. Available pack sizes: 0,25g, 0,5g, 1g, 5g, 2g. Offered by: Biosynth.

brandBiosynth
catalog numberFI73263-0,25g
cas100286-90-6
size0,25g

Available pack sizes

brand size price
Biosynth 0,25g price on request
Biosynth 0,5g price on request
Biosynth 1g price on request
Biosynth 5g price on request
Biosynth 2g price on request

properties

categoryResearch Chemicals
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Irinotecan hydrochloride (anhydrous) is a hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an antineoplastic agent, a prodrug, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. It contains an irinotecan(1+).

Source: ChEBI

Identity
Molecular formulaC33H39ClN4O6
Molecular weight623.1 g/mol
IUPAC name[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride
InChIKeyGURKHSYORGJETM-WAQYZQTGSA-N
SMILESCCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl

Computed by PubChem (NCBI)

Synonyms: Irinotecan hydrochloride, Campto, Camptothecin 11 hydrochloride, Irinotecan hydrochloride anhydrous, 7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxy camptothecin hydrochloride, irinotecan hydrochloride (anhydrous), Irinomedac, Irinotecan hydrochloide, Irinotecan Hydrochloride 40 mg/2 mL, Irinotecan Hydrochloride 100 mg/5 mL

Also listed as

Irinotecan hydrochloride, 95% Combi-blocks CAS 100286-90-6
Irinotecan HCl Chemat Brand CAS 100286-90-6
Irinotecan Hydrochloride/ 99.93% (existing batch purity) TargetMol CAS 100286-90-6
Irinotecan hydrochloride Thermo Scientific (Alfa Aesar) CAS 100286-90-6
Irinotecan HCl 98% Ambeed CAS 100286-90-6
(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate hydrochloride, 98%, 98% Chemat CAS 100286-90-6
Irinotecan (hydrochloride), 99.89% MedChemExpress CAS 100286-90-6
Irinotecan (hydrochloride) (Standard) MedChemExpress CAS 100286-90-6