Itraconazole (Standard)
cas: 84625-61-6 — see every product listed under this CAS number, including other names
Itraconazole (Standard) (CAS 84625-61-6) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 25 mg, 100 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-17514R-10 mg |
| cas | 84625-61-6 |
| size | 10 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 282.54 Pln | |
| MedChemExpress | 25 mg | 380.06 Pln | |
| MedChemExpress | 100 mg | 695.86 Pln | |
| MedChemExpress | 50 mg | 505.45 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Itraconazole is an N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. It has a role as a Hedgehog signaling pathway inhibitor, a P450 inhibitor and an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor. It is a dichlorobenzene, an aromatic ether, a member of triazoles, a dioxolane, a N-arylpiperazine, a cyclic ketal, a conazole antifungal drug and a triazole antifungal drug.
Source: ChEBI
| Molecular formula | C35H38Cl2N8O4 |
|---|---|
| Molecular weight | 705.6 g/mol |
| IUPAC name | 2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one |
| InChIKey | VHVPQPYKVGDNFY-ZPGVKDDISA-N |
| SMILES | CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[C@H]5CO[C@](O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl |
Computed by PubChem (NCBI)
Synonyms:
itraconazole, Oriconazole, Sporanox, Itraconazol, Canditral, Traconal, Triasporin, Sporonox, Fungitraxx, Itraconazolo