Ivosidenib 98%
cas: 1448347-49-6 — see every product listed under this CAS number, including other names
Ivosidenib 98% (CAS 1448347-49-6) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 50mg, 100mg, 250mg, 1g, 1mg, 5mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A153326-25mg |
| cas | 1448347-49-6 |
| size | 25mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 25mg | 253.56 Pln | |
| Ambeed | 50mg | 325.88 Pln | |
| Ambeed | 100mg | 481.62 Pln | |
| Ambeed | 250mg | 765.31 Pln | |
| Ambeed | 1g | 1955.69 Pln | |
| Ambeed | 1mg | 175.69 Pln | |
| Ambeed | 5mg | 197.94 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 1-2 weeks |
| ambeed catalog no. | A153326 |
Ivosidenib is a tertiary carboxamide resulting from the formal condensation of the carboxy group of (2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidine-2-carboxylic acid with the secondary amino group of (2S)-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-2-[(5-fluoropyridin-3-yl)amino]acetamide. It is approved by the FDA for the treatment of acute myeloid leukemia (AML) in patients with an isocitrate dehydrogenase-1 (IDH1) mutation. It has a role as an EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor and an antineoplastic agent. It is a secondary carboxamide, a tertiary carboxamide, a cyanopyridine, an organofluorine compound, a member of pyrrolidin-2-ones and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C28H22ClF3N6O3 |
|---|---|
| Molecular weight | 583.0 g/mol |
| IUPAC name | (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide |
| InChIKey | WIJZXSAJMHAVGX-DHLKQENFSA-N |
| SMILES | C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N |
Computed by PubChem (NCBI)