Ixabepilone, >95% (HPLC)

cas: 219989-84-1 — see every product listed under this CAS number, including other names

Ixabepilone, >95% (HPLC) (CAS 219989-84-1) is a chemical reagent available from Chemat. Available pack sizes: 2,5mg, 25mg. Offered by: TRC.

brandTRC
catalog numberTRC-I941990-2.5MG
cas219989-84-1
size2,5mg
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Available pack sizes

brand size price
TRC 2,5mg price on request
TRC 25mg price on request

properties

purity>95% (HPLC)
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Ixabepilone is a macrocycle that is a lactam analogue of epothilone B. Binds directly to beta-tubulin subunits on microtubules, leading to suppression of microtubule dynamics. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is a lactam, an epoxide, a member of 1,3-thiazoles, a macrocycle and a beta-hydroxy ketone.

Source: ChEBI

Identity
Molecular formulaC27H42N2O5S
Molecular weight506.7 g/mol
IUPAC name(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
InChIKeyFABUFPQFXZVHFB-PVYNADRNSA-N
SMILESC[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C

Computed by PubChem (NCBI)

Synonyms: Ixabepilone, Azaepothilone B, Ixempra, Aza-epothilone B, Ixempra kit, ixabepilona, ixabepilonum, Epothilone-B BMS 247550, Ixabepilone [INN], Ixempra (TN)
Related forms of this compound
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(Z)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione C27H42N2O5S
(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-[2-(trideuteriomethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione C27H42N2O5S
Isomers (same molecular formula)
(1R,2R,6S,7S,8R,11S,15S)-2,7,11-trihydroxy-2,6,8,10,10-pentamethyl-15-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-14-azabicyclo[11.3.1]heptadec-13-en-9-one C27H42N2O5S
(1S,2R,6S,7S,8R,11S,15S)-2,7,11-trihydroxy-2,6,8,10,10-pentamethyl-15-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-14-azabicyclo[11.3.1]heptadec-13-en-9-one C27H42N2O5S

Also listed as

Ixabepilone Chemat Brand CAS 219989-84-1
Ixabepilone/ 98.6% (existing batch purity) TargetMol CAS 219989-84-1
Ixabepilone 98% Ambeed CAS 219989-84-1
(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione, 98%, 98% Chemat CAS 219989-84-1
Ixabepilone (Standard) MedChemExpress CAS 219989-84-1
Ixabepilone, 99.93% MedChemExpress CAS 219989-84-1
IXABEPILONE, 98% Fluorochem CAS 219989-84-1