Products 1072833-77-2
CAS 1072833-77-2 appears in our catalog under these names: Ixazomib, Ixazomib/ 98.07% (existing batch purity), MLN2238, Ixazomib [MLN2238], Ixazomib 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 100mg, 10mg, 50mg, 1mg, 5mg, 25mg, 500mg, 10mM (in 1ml dmso).
Ixazomib is a glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma. It has a role as an antineoplastic agent, a drug metabolite, a proteasome inhibitor, an apoptosis inducer and an orphan drug. It is a member of benzamides, a dichlorobenzene, a glycine derivative and a member of boronic acids.
Source: ChEBI
| Molecular formula | C14H19BCl2N2O4 |
|---|---|
| Molecular weight | 361.0 g/mol |
| IUPAC name | [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid |
| InChIKey | MXAYKZJJDUDWDS-LBPRGKRZSA-N |
| SMILES | B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O |
Computed by PubChem (NCBI)
Synonyms:
Ixazomib, [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid, [(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid, ixazomibum, ((1R)-1-((2-((2,5-dichlorobenzoyl)amino)acetyl)amino)-3-methylbutyl)boronic acid, ((1R)-1-(2-((2,5-dichlorophenyl)formamido)acetamido)-3-methylbutyl)boronic acid, (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid, (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid, Ixazomib [INN], Ixozamib