JHU-083
cas: 1998725-11-3 — see every product listed under this CAS number, including other names
JHU-083 (CAS 1998725-11-3) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 25mg, 10mg, 50mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | YED72511-5mg |
| cas | 1998725-11-3 |
| size | 5mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 5mg | price on request | |
| Biosynth | 25mg | price on request | |
| Biosynth | 10mg | price on request | |
| Biosynth | 50mg | price on request |
properties
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| purity | No data |
| delivery time | 3-4 Weeks |
JHU083 is an ethyl ester resulting from the formal condensation of the carboxy group of L-leucyl-6-diazo-5-oxo-L-norleucine with ethanol. It is a glutaminase inhibitor and a prodrug of 6-diazo-5-oxo-L-norleucine that exhibits antineoplastic activity. It has a role as an antineoplastic agent, a prodrug and an EC 3.5.1.2 (glutaminase) inhibitor. It is a secondary carboxamide, a ketone, an ethyl ester, a L-leucine derivative and a diazo compound.
Source: ChEBI
| Molecular formula | C14H24N4O4 |
|---|---|
| Molecular weight | 312.36 g/mol |
| IUPAC name | ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate |
| InChIKey | YZRCHOFKIPHQBW-RYUDHWBXSA-N |
| SMILES | CCOC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CC(C)C)N |
Computed by PubChem (NCBI)
Synonyms:
ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate, ethyl (2S)-2-(((2S)-2-amino-4-methylpentanoyl)amino)-6-diazo-5-oxohexanoate, ethyl (2S)-2-{[(2S)-2-amino-4-methylpentanoyl]amino}-6-diazo-5-oxohexanoate, L-Norleucine, L-leucyl-6-diazo-5-oxo-, ethyl ester, orb1707162, orb3054177, ethyl (S)-2-((S)-2-amino-4-methylpentanamido)-6-diazo-5-oxohexanoate, ethyl L-leucyl-6-diazo-5-oxo-L-norleucinate