Products 109844-92-0

CAS 109844-92-0 appears in our catalog under these names: LCS3/ 99.68% (existing batch purity), LCS3, N-(4-chlorophenyl)-5-nitro-2-furancarboxamide, LCS3, 99.43%. Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 10 mg.

LCS3/ 99.68% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 518.63
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LCS3
GLPBio
  • size: 1mg, 10mg, 5mg
  • Variants: 3
from 536.19
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N-(4-chlorophenyl)-5-nitro-2-furancarboxamide
Chemat
  • size: 1mg, 100mg, 500mg, 5mg
  • Variants: 7
from 395.60
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LCS3, 99.43%
MedChemExpress
  • size: 10 mg, 25 mg, 50 mg, 10mM/1mL
  • Variants: 6
from 839.82
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Structural formula: {0} (CAS {1})

LCS3 is a reversible and uncompetitive glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) inhibitor (IC50=3.3 uM and 3.8 uM, respectively). LCS3 shows anti-tumor activity, and induces apoptosis. LCS3 can be used in lung adenocarcinoma (LUAD) research.

Source: ChEBI

Identity
Molecular formulaC11H7ClN2O4
Molecular weight266.64 g/mol
IUPAC nameN-(4-chlorophenyl)-5-nitrofuran-2-carboxamide
InChIKeyJDBZJNUHQINERI-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])Cl

Computed by PubChem (NCBI)

Synonyms: N-(4-chlorophenyl)-5-nitrofuran-2-carboxamide, N-(4-chlorophenyl)-5-nitro-2-furancarboxamide, N-(4-chlorophenyl)-5-nitro-2-furamide, Cambridge id 5181524, Oprea1_138342, Oprea1_207704, orb1689577, N-(4-chlorophenyl)(5-nitro(2-furyl))carboxamide, 5-nitro-furan-2-carboxylic acid-(4-chloro-anilide), <p>LCS3</p>
Isomers (same molecular formula)
1-(3-chlorophenyl)-4-hydroxy-6-oxopyridazine-3-carboxylic acid C11H7ClN2O4
methyl 2-chloro-6-nitroquinoline-4-carboxylate C11H7ClN2O4