LY3009120, 98.66%
cas: 1454682-72-4 — see every product listed under this CAS number, including other names
LY3009120, 98.66% (CAS 1454682-72-4) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 25 mg, 100 mg, 10mM/1mL, 5 mg, 200 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12558-10 mg |
| cas | 1454682-72-4 |
| size | 10 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 593.69 Pln | |
| MedChemExpress | 25 mg | 1229.92 Pln | |
| MedChemExpress | 100 mg | 3477.61 Pln | |
| MedChemExpress | 10mM/1mL | 412.57 Pln | |
| MedChemExpress | 5 mg | 384.71 Pln | |
| MedChemExpress | 200 mg | 5158.74 Pln | |
| MedChemExpress | 50 mg | 2233.02 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 98.66% |
LY3009120 is a member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties. It has a role as an autophagy inducer, a necroptosis inhibitor, an antineoplastic agent, an apoptosis inducer and a B-Raf inhibitor. It is a member of phenylureas, an aminotoluene, an aromatic amine, a pyridopyrimidine, a secondary amino compound, a biaryl and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H29FN6O |
|---|---|
| Molecular weight | 424.5 g/mol |
| IUPAC name | 1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea |
| InChIKey | HHCBMISMPSAZBF-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F |
Computed by PubChem (NCBI)