cas: 156897-06-2 — see every product listed under this CAS number, including other names
Licofelone (CAS 156897-06-2) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mM (in 1ml dmso), 50mg, 1mg, 10mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC16721-5 |
| cas | 156897-06-2 |
| size | 5mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 5mg | 667.25 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 704.69 Pln | |
| GLPBio | 50mg | 2150.97 Pln | |
| GLPBio | 1mg | 657.89 Pln | |
| GLPBio | 10mg | 938.72 Pln | |
| GLPBio | 5mg | 700.01 Pln | |
| Biosynth | 50mg | price on request | |
| Biosynth | 10mg | price on request |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Licofelone is a member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine substituted by methyl, methyl, carboxymethyl, 4-chlorophenyl, and phenyl groups at positions 2, 2, 5, 6, and 7, respectively. It is a dual inhibitor of cyclooxygenase isoforms and 5-lipoxygenase and is under development for treatment of osteoarthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antineoplastic agent, an anticonvulsant, a neuroprotective agent and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a monocarboxylic acid, a member of pyrrolizines and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C23H22ClNO2 |
|---|---|
| Molecular weight | 379.9 g/mol |
| IUPAC name | 2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid |
| InChIKey | UAWXGRJVZSAUSZ-UHFFFAOYSA-N |
| SMILES | CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C |
Computed by PubChem (NCBI)