Linifanib (Standard)
cas: 796967-16-3 — see every product listed under this CAS number, including other names
Linifanib (Standard) (CAS 796967-16-3) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-50751R-Get quote |
| cas | 796967-16-3 |
| size | Get quote |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | Get quote | price on request |
properties
| delivery time | to confirm by Chemat |
|---|---|
| purity | no data |
Linifanib is a member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 2-fluoro-5-methylphenyl group, while the other is substituted by a p-(3-amino-1H-indazol-4-yl)phenyl group. It is a potent, selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases. It has a role as an antineoplastic agent, an angiogenesis inhibitor and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a member of phenylureas, an aromatic amine and a member of indazoles.
Source: ChEBI
| Molecular formula | C21H18FN5O |
|---|---|
| Molecular weight | 375.4 g/mol |
| IUPAC name | 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea |
| InChIKey | MPVGZUGXCQEXTM-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N |
Computed by PubChem (NCBI)
Synonyms:
Linifanib, 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea, 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea, linifanibum, N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea, N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea, Urea, N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)-, multitargeted receptor tyrosine kinase inhibitor ABT-869, Linifanib (ABT-869)