Products 796967-16-3

CAS 796967-16-3 appears in our catalog under these names: Linifanib, >95% (HPLC), Linifanib/ 99.29% (existing batch purity), Linifanib (ABT–869), Linifanib, >95.0%(HPLC)(qNMR), Linifanib. Offered by: TRC, TargetMol, GLPBio, TCI, Chemat. Available pack sizes: 1mg, 25mg, 5mg, 10mg, 50mg, 100mg, 200mg, 500mg.

Linifanib, >95% (HPLC)
TRC
  • size: 1mg, 25mg
  • Variants: 2
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Linifanib/ 99.29% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 465.53
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Linifanib (ABT–869)
GLPBio
  • size: 100mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 3
from 625.12
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Linifanib, >95.0%(HPLC)(qNMR)
TCI
  • size: 100mg
  • Variants: 1
from 1470.59
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Linifanib
Chemat
  • size: 10mg, 1mg, 5mg
  • Variants: 3
from 994.04
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Linifanib 98+%
Ambeed
  • size: 1mg, 5mg, 10mg, 50mg
  • Variants: 6
from 186.81
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Linifanib (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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Linifanib, 99.72%
MedChemExpress
  • size: 200 mg, 100 mg, 10mM/1mL, 10 mg
  • Variants: 8
from 384.71
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Linifanib (GMP), 99.9%
MedChemExpress
  • size: 10 mg, 50 mg, 100 mg
  • Variants: 3
from 6166.49
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Structural formula: {0} (CAS {1})

Linifanib is a member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 2-fluoro-5-methylphenyl group, while the other is substituted by a p-(3-amino-1H-indazol-4-yl)phenyl group. It is a potent, selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinases. It has a role as an antineoplastic agent, an angiogenesis inhibitor and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a member of phenylureas, an aromatic amine and a member of indazoles.

Source: ChEBI

Identity
Molecular formulaC21H18FN5O
Molecular weight375.4 g/mol
IUPAC name1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
InChIKeyMPVGZUGXCQEXTM-UHFFFAOYSA-N
SMILESCC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N

Computed by PubChem (NCBI)

Synonyms: Linifanib, 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea, 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea, linifanibum, N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea, N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea, Urea, N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)-, multitargeted receptor tyrosine kinase inhibitor ABT-869, Linifanib (ABT-869)