Losmapimod, 99% (HPLC)
cas: 585543-15-3 — see every product listed under this CAS number, including other names
Losmapimod, 99% (HPLC) (CAS 585543-15-3) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F953474-5MG |
| cas | 585543-15-3 |
| size | 5mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 5mg | 206.20 Pln | |
| Fluorochem | 10mg | 263.47 Pln | |
| Fluorochem | 25mg | 445.69 Pln | |
| Fluorochem | 50mg | 695.61 Pln | |
| Fluorochem | 100mg | 1122.54 Pln | |
| Fluorochem | 250mg | 1841.04 Pln |
properties
| purity | 99% (HPLC) |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Losmapimod is a secondary carboxamide resulting from the formal condensation of the carboxy group of 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]pyridine-3-carboxylic acid with the amino group of neopentylamine. It is a potent p38alpha/beta mitogen activated protein kinase inhibitor which was previously in clinical trials for the treatment of facioscapulohumeral muscular dystrophy trial now discontinued due to not achieving its primary endpoint. It has a role as a nootropic agent, an anti-inflammatory agent, a cardioprotective agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a secondary carboxamide, a member of benzamides, a pyridinecarboxamide, a member of toluenes, a phenylpyridine, a member of cyclopropanes and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C22H26FN3O2 |
|---|---|
| Molecular weight | 383.5 g/mol |
| IUPAC name | 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide |
| InChIKey | KKYABQBFGDZVNQ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1F)C(=O)NC2CC2)C3=NC=C(C=C3)C(=O)NCC(C)(C)C |
Computed by PubChem (NCBI)