Products 510-74-7
CAS 510-74-7 appears in our catalog under these names: AMI-193, >95% (HPLC), AMI-193/ 99.04% (existing batch purity), AMI–193, Spiramide, 98%, 98%, Spiramide, 99.23%. Offered by: TRC, TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 50mg, 5mg, 10mg, 25mg, 100mg, 10mM/1mL, 50 mg, 25 mg.
Spiramide is an azaspiro compound that consists of 1,3,8-triazaspiro[4.5]decan-4-one having a phenyl group attached to N-1 and a 3-(4-fluorophenoxy)propyl attached to N-8. Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spiperone but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behaviour. It has a role as a serotonergic antagonist and a dopaminergic antagonist. It is a member of piperidines, an aromatic ether, an azaspiro compound, an organofluorine compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C22H26FN3O2 |
|---|---|
| Molecular weight | 383.5 g/mol |
| IUPAC name | 8-[3-(4-fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| InChIKey | FJUKDAZEABGEIH-UHFFFAOYSA-N |
| SMILES | C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCOC4=CC=C(C=C4)F |
Computed by PubChem (NCBI)
Synonyms:
Spiramide, Espiramida, Spiramidum, 8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-(3-(4-fluorophenoxy)propyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 8-(3-(4-Fluorophenoxy)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one, 8-(3-(4-Fluorophenoxy) propyl)-1-phenyl-1,3,8-triazaspiro(4, 5)decan-4-one, Spiramide [INN], Fluroxyspiramine, Spiramidum [INN-Latin]