Products 219832-49-2

CAS 219832-49-2 appears in our catalog under these names: 4-Methyl-N-(2-((2-((4-methylphenyl)sulfonamido)benzylidene)amino)phenyl)benzenesulfonamide, 97%, 97%, MP-A08/ 98.04% (existing batch purity), MP–A08, MP-A08, MP-A08, 98.0%. Offered by: Chemat, TargetMol, GLPBio, Biosynth, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 1mg, 10mM (in 1ml dmso).

4-Methyl-N-(2-((2-((4-methylphenyl)sulfonamido)benzylidene)amino)phenyl)benzenesulfonamide, 97%, 97%
Chemat
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 482.00
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MP-A08/ 98.04% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 405.71
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MP–A08
GLPBio
  • size: 1mg, 10mg, 100mg, 10mM (in 1ml dmso)
  • Variants: 6
from 625.12
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MP-A08
Biosynth
  • size: 25mg, 50mg, 100mg
  • Variants: 3
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MP-A08, 98.0%
MedChemExpress
  • size: 25 mg, 1 mg, 5 mg, 10 mg
  • Variants: 6
from 287.18
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Structural formula: {0} (CAS {1})

MP-A08 is a sulfonamide that consists of two moieties of 4-methyl-N-phenylbenzenesulfonamide connected to each other at position 2 by an aldimine linker. It is a ATP-competitive inhibitor of sphingosine kinase that targets both SK1 and SK2 (Ki values of 27 M and 6.9 M, respectively) and exhibits anti-cancer properties. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an apoptosis inducer and an EC 2.7.1.91 (sphingosine kinase) inhibitor. It is a member of toluenes, an aldimine and a sulfonamide.

Source: ChEBI

Identity
Molecular formulaC27H25N3O4S2
Molecular weight519.6 g/mol
IUPAC name4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide
InChIKeyFLDBNMYJUMAXDQ-UHFFFAOYSA-N
SMILESCC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C=NC3=CC=CC=C3NS(=O)(=O)C4=CC=C(C=C4)C

Computed by PubChem (NCBI)

Synonyms: orb1308016