cas: 441798-33-0 — see every product listed under this CAS number, including other names
Macitentan (CAS 441798-33-0) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 0,1g, 0,25g. Offered by: Chemat Brand, Mikromol, GLPBio, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | AO-M0072.00 |
| cas | 441798-33-0 |
| size | on request |
| availability | In stock |
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| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Chemat Brand | on request | price on request | |
| Mikromol | 250mg | price on request | |
| GLPBio | 100mg | 1214.87 Pln | |
| GLPBio | 25mg | 1158.70 Pln | |
| GLPBio | 5mg | 648.53 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 784.26 Pln | |
| Biosynth | 0,1g | price on request | |
| Biosynth | 0,25g | price on request | |
| Biosynth | 0,5g | price on request | |
| Biosynth | 1g | price on request | |
| Biosynth | 2g | price on request |
| delivery time | To be confirmed by Chemat |
|---|---|
| purity | No data |
Macitentan is a member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an antihypertensive agent, an endothelin receptor antagonist and an orphan drug. It is an aromatic ether, a ring assembly, an organobromine compound, a member of pyrimidines and a member of sulfamides. It is functionally related to an ethylene glycol and an ACT-132577.
Source: ChEBI
| Molecular formula | C19H20Br2N6O4S |
|---|---|
| Molecular weight | 588.3 g/mol |
| IUPAC name | 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine |
| InChIKey | JGCMEBMXRHSZKX-UHFFFAOYSA-N |
| SMILES | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br |
Computed by PubChem (NCBI)