Products 441798-33-0

CAS 441798-33-0 appears in our catalog under these names: Macitentan, Macitentan, >95% (HPLC), Macitentan/ 99.81% (existing batch purity), Macitentan - Bio-X â„¢, Macitentan 98%. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 100mg, 25mg, 5mg, 250mg, 10mg, 50mg, 500mg.

Macitentan
Chemat Brand, Mikromol, GLPBio
  • size: on request, 250mg, 100mg, 25mg
  • Variants: 12
from 648.53
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Macitentan, >95% (HPLC)
TRC
  • size: 100mg, 25mg, 5mg
  • Variants: 3
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Macitentan/ 99.81% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 5
from 465.53
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Macitentan - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Macitentan 98%
Ambeed
  • size: 1mg, 5mg, 50mg, 100mg
  • Variants: 7
from 120.06
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Macitentan, 99.87%
MedChemExpress
  • size: 10mM/1mL, 5 mg, 50 mg, 100 mg
  • Variants: 5
from 384.71
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Macitentan (Standard), 99.79%
MedChemExpress
  • size: 25 mg, 5 mg, 10 mg, 100 mg
  • Variants: 5
from 765.52
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Macitentan-d7
Chemat Brand
  • size: on request
  • Variants: 1
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Macitentan is a member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an antihypertensive agent, an endothelin receptor antagonist and an orphan drug. It is an aromatic ether, a ring assembly, an organobromine compound, a member of pyrimidines and a member of sulfamides. It is functionally related to an ethylene glycol and an ACT-132577.

Source: ChEBI

Identity
Molecular formulaC19H20Br2N6O4S
Molecular weight588.3 g/mol
IUPAC name5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
InChIKeyJGCMEBMXRHSZKX-UHFFFAOYSA-N
SMILESCCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br

Computed by PubChem (NCBI)

Synonyms: Macitentan, Opsumit, Actelion-1, macitentanum, OPSYNVI COMPONENT MACITENTAN, C19H20Br2N6O4S, Macitentan [INN], Macitentan [USAN:INN], Opsumit (TN), Macitentan (Standard)
Related forms of this compound
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxy-1,1,2,2-tetradeuterioethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine C19H20Br2N6O4S