Manumycin A
cas: 52665-74-4 — see every product listed under this CAS number, including other names
Manumycin A (CAS 52665-74-4) is a chemical reagent available from Chemat. Available pack sizes: 0,5mg, 2,5mg, 1mg, 5mg. Offered by: TRC, TargetMol, GLPBio.
| brand | TRC |
|---|---|
| catalog number | TRC-M186000-0.5MG |
| cas | 52665-74-4 |
| size | 0,5mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 0,5mg | price on request | |
| TRC | 2,5mg | price on request | |
| TargetMol | 1mg | 1953.02 Pln | |
| TargetMol | 5mg | 6422.79 Pln | |
| GLPBio | 1mg | 1144.66 Pln | |
| GLPBio | 5mg | 3129.19 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Manumycin A is a polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties. It has a role as an antiatherosclerotic agent, an antimicrobial agent, an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor, an EC 1.8.1.9 (thioredoxin reductase) inhibitor, an apoptosis inducer, a marine metabolite and a bacterial metabolite. It is a secondary carboxamide, a polyketide, a tertiary alcohol, an organic heterobicyclic compound, an epoxide and an enamide.
Source: ChEBI
| Molecular formula | C31H38N2O7 |
|---|---|
| Molecular weight | 550.6 g/mol |
| IUPAC name | (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide |
| InChIKey | TWWQHCKLTXDWBD-MVTGTTCWSA-N |
| SMILES | CCCC[C@@H](C)/C=C(\C)/C=C(\C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O |
Computed by PubChem (NCBI)