Products 52665-74-4
CAS 52665-74-4 appears in our catalog under these names: Manumycin a, 95%, Manumycin A, Manumycin A, Manumycin A, 98.00%, Manumycin A, ≥98%, ≥98%. Offered by: Combi-blocks, TRC, TargetMol, GLPBio, Chemat. Available pack sizes: 1mg, 5mg, 0,5mg, 2,5mg, 10mg, 10 mg, 1 mg, 5 mg.
Manumycin A is a polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties. It has a role as an antiatherosclerotic agent, an antimicrobial agent, an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor, an EC 1.8.1.9 (thioredoxin reductase) inhibitor, an apoptosis inducer, a marine metabolite and a bacterial metabolite. It is a secondary carboxamide, a polyketide, a tertiary alcohol, an organic heterobicyclic compound, an epoxide and an enamide.
Source: ChEBI
| Molecular formula | C31H38N2O7 |
|---|---|
| Molecular weight | 550.6 g/mol |
| IUPAC name | (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide |
| InChIKey | TWWQHCKLTXDWBD-MVTGTTCWSA-N |
| SMILES | CCCC[C@@H](C)/C=C(\C)/C=C(\C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O |
Computed by PubChem (NCBI)