CAS 503-49-1 appears in our catalog under these names: 3-Hydroxy-3-methylglutaric acid, 95%, 3-Hydroxy-3-methylpentane-1,5-dioic Acid, >95% (HPLC), Meglutol/ 99.73% (existing batch purity), 3-Hydroxy-3-methylglutaric acid, 95.00%, 3-Hydroxy-3-methylglutaric acid. Offered by: Combi-blocks, TRC, TargetMol, Chemat, Biosynth. Available pack sizes: 100mg, 1g, 500mg, 50mg, 5g, 10g, 250mg, 100 mg.
3-hydroxy-3-methylglutaric acid is a dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura. It has a role as an antimetabolite, an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor, an anticholesteremic drug, a plant metabolite and a human metabolite. It is a tertiary alcohol, a dicarboxylic acid and a 3-hydroxy carboxylic acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 3-hydroxy-3-methylglutarate(1-).
Source: ChEBI
| Molecular formula | C6H10O5 |
|---|---|
| Molecular weight | 162.14 g/mol |
| IUPAC name | 3-hydroxy-3-methylpentanedioic acid |
| InChIKey | NPOAOTPXWNWTSH-UHFFFAOYSA-N |
| SMILES | CC(CC(=O)O)(CC(=O)O)O |
Computed by PubChem (NCBI)