Mevastatin

cas: 73573-88-3 — see every product listed under this CAS number, including other names

Mevastatin (CAS 73573-88-3) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 10mg, 10mM (in 1ml dmso), 50mg, 5g, 2g, 10g, 1x100mg. Offered by: Mikromol, LoGiCal, Dr. Ehrenstorfer, GLPBio.

brandMikromol
catalog numberMM0377.00
cas73573-88-3
size100mg
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Available pack sizes

brand size price
Mikromol 100mg price on request
LoGiCal 10mg price on request
Dr. Ehrenstorfer 100mg price on request
GLPBio 10mM (in 1ml dmso) 597.04 Pln
GLPBio 50mg 606.40 Pln
Biosynth 5g price on request
Biosynth 2g price on request
Biosynth 10g price on request
HPC Standards 1x100mg 480.40 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Mevastatin is a carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. It has a role as an antifungal agent, an apoptosis inducer, a fungal metabolite, a Penicillium metabolite and an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor. It is a member of hexahydronaphthalenes, a polyketide, a carboxylic ester, a member of 2-pyranones and a statin (naturally occurring).

Source: ChEBI

Identity
Molecular formulaC23H34O5
Molecular weight390.5 g/mol
IUPAC name[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
InChIKeyAJLFOPYRIVGYMJ-INTXDZFKSA-N
SMILESCC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O

Computed by PubChem (NCBI)

Synonyms: Mevastatin, compactin, Mevastatina, Mevastatine, Mevastatinum, Antibiotic ML 236B, 6-demethylmevinolin, Mevastatin [INN], Mevastatinum [INN-Latin], Compactin (penicillium)
Isomers (same molecular formula)
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid C23H34O5
(Z)-3,3,4,4-tetradeuterio-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid C23H34O5
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2-methylpropanoate C23H34O5
2-[[(1S,2S,3aR,9aR)-2-hydroxy-1-[(3R)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid C23H34O5
2-[[(1S,2S,3aR,9aR)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid C23H34O5
2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid C23H34O5
3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one C23H34O5
3-[(3S,5R,8R,9S,10S,13R,14S,16S,17R)-3,14,16-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one C23H34O5
2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3R)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid C23H34O5
(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoic acid C23H34O5
(3E,4S)-3-[2-[(2aS,4aS,5R,8aS,8bR)-2a-hydroxy-8b-(hydroxymethyl)-2,2,4a-trimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-1H-cyclobuta[a]naphthalen-5-yl]ethylidene]-4-hydroxyoxolan-2-one C23H34O5
3-[(3S,5S,8R,9S,10R,13R,14S,17R)-3,5,14-trihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one C23H34O5

Also listed as

Mevastatin (Compactin) Chemat Brand CAS 73573-88-3
Lovastatin EP Impurity A (Mevastatin) Chemat Brand CAS 73573-88-3
Mevastatin, >95% (HPLC) TRC CAS 73573-88-3
Mevastatin/ 97.96% (existing batch purity) TargetMol CAS 73573-88-3
Mevastatin, 98% Thermo Scientific (Alfa Aesar) CAS 73573-88-3
Mevastatin, >98.0%(HPLC) TCI CAS 73573-88-3
Mevastatin, 98.00% Chemat CAS 73573-88-3
Mevastatin - Bio-X â„¢ Biosynth CAS 73573-88-3
Mevastatin 95% Ambeed CAS 73573-88-3
Mevastatin 1PC X 50MG Sigma-Aldrich CAS 73573-88-3
(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate, 95%, 95% Chemat CAS 73573-88-3
Mevastatin, BioScience Grade, 10 mg Roth CAS 73573-88-3
Mevastatin, 99.46% MedChemExpress CAS 73573-88-3
Mevastatin (Standard) MedChemExpress CAS 73573-88-3
Mevastatin, 95% Fluorochem CAS 73573-88-3