N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide, 99%

cas: 1421373-65-0 — see every product listed under this CAS number, including other names

N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide, 99% (CAS 1421373-65-0) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 250mg, 1g, 5g, 10g, 25g, 50g. Offered by: Chemat.

brandChemat
catalog numberCh110C5D-100mg
cas1421373-65-0
size100mg
availability 54.9g
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Available pack sizes

brand size price
Chemat 100mg 88.40 Pln
Chemat 250mg 98.00 Pln
Chemat 1g 146.00 Pln
Chemat 5g 304.40 Pln
Chemat 10g 477.20 Pln
Chemat 25g 890.00 Pln
Chemat 50g 1614.80 Pln

properties

purity99%
delivery time3 weeks

Osimertinib is a member of the class of aminopyrimidines that is 4-(1-methylindol-3-yl)pyrimidin-2-amine in which one of the amino hydrogens is replaced by a 2-methoxy-4-[2-(dimethylamino)ethyl](methyl)amino-5-acrylamidophenyl group. Used (as the mesylate salt) for treatment of EGFR T790M mutation positive non-small cell lung cancer. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is a secondary carboxamide, a member of acrylamides, a member of indoles, a monomethoxybenzene, an aminopyrimidine, a substituted aniline, a secondary amino compound, a tertiary amino compound and a biaryl. It is a conjugate base of an osimertinib(1+).

Source: ChEBI

Identity
Molecular formulaC28H33N7O2
Molecular weight499.6 g/mol
IUPAC nameN-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
InChIKeyDUYJMQONPNNFPI-UHFFFAOYSA-N
SMILESCN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

Computed by PubChem (NCBI)

Synonyms: osimertinib, Mereletinib, osimertinibum, Osimertinib [USAN], Osimertinib (AZD9291), Mereletinib [INN], Osimertinib (Standard), OSIMERTINIB [MI], OSIMERTINIB [INN], Osimertinib; AZD 9291
Related forms of this compound
N-[2-[2-[bis(trideuteriomethyl)amino]ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide C28H33N7O2
N-[2-[2-(dimethylamino)ethyl-(trideuterio(113C)methyl)amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide C28H33N7O2
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-[1-(trideuteriomethyl)indol-3-yl]pyrimidin-2-yl]amino]phenyl]prop-2-enamide C28H33N7O2
3,3-dideuterio-N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-[1-(trideuteriomethyl)indol-3-yl]pyrimidin-2-yl]amino]phenyl]prop-2-enamide C28H33N7O2
Isomers (same molecular formula)
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(3-methylindol-1-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide C28H33N7O2

Also listed as

Osimertinib（AZD9291) Chemat Brand CAS 1421373-65-0
Osimertinib (AZD9291) Chemat Brand CAS 1421373-65-0
AZD 9291(Osimertinib), >95% (HPLC) TRC CAS 1421373-65-0
AZD 9291 (Osimertinib), >95% (HPLC) TRC CAS 1421373-65-0
Osimertinib Mikromol CAS 1421373-65-0
Osimertinib/ 99.83% (existing batch purity) TargetMol CAS 1421373-65-0
AZD–9291 GLPBio CAS 1421373-65-0
AZD 9291 Biosynth CAS 1421373-65-0
Osimertinib, 98.00% Chemat CAS 1421373-65-0
N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide, 98%, 98% Chemat CAS 1421373-65-0
Osimertinib, 99.99% MedChemExpress CAS 1421373-65-0
Osimertinib (Standard), 99.69% MedChemExpress CAS 1421373-65-0
Osimertinib, 98% Ambeed CAS 1421373-65-0
N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide, 98% BLDpharm CAS 1421373-65-0