cas: 1421373-65-0 — see every product listed under this CAS number, including other names
Osimertinib (CAS 1421373-65-0) is a chemical reagent available from Chemat. Available pack sizes: 250mg. Offered by: Mikromol.
| brand | Mikromol |
|---|---|
| catalog number | MM3918.00-0250 |
| cas | 1421373-65-0 |
| size | 250mg |
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| brand | size | price | |
|---|---|---|---|
| Mikromol | 250mg | price on request |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Osimertinib is a member of the class of aminopyrimidines that is 4-(1-methylindol-3-yl)pyrimidin-2-amine in which one of the amino hydrogens is replaced by a 2-methoxy-4-[2-(dimethylamino)ethyl](methyl)amino-5-acrylamidophenyl group. Used (as the mesylate salt) for treatment of EGFR T790M mutation positive non-small cell lung cancer. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is a secondary carboxamide, a member of acrylamides, a member of indoles, a monomethoxybenzene, an aminopyrimidine, a substituted aniline, a secondary amino compound, a tertiary amino compound and a biaryl. It is a conjugate base of an osimertinib(1+).
Source: ChEBI
| Molecular formula | C28H33N7O2 |
|---|---|
| Molecular weight | 499.6 g/mol |
| IUPAC name | N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide |
| InChIKey | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
Computed by PubChem (NCBI)