NP-12
cas: 1353564-66-5 — see every product listed under this CAS number, including other names
NP-12 (CAS 1353564-66-5) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Creative Peptides.
| brand | Creative Peptides |
|---|---|
| catalog number | CP-R1566 |
| cas | 1353564-66-5 |
| size | on request |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Creative Peptides | on request | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of benzenes, a member of naphthalenes and a thiadiazolidine.
Source: ChEBI
| Molecular formula | C19H14N2O2S |
|---|---|
| Molecular weight | 334.4 g/mol |
| IUPAC name | 4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione |
| InChIKey | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43 |
Computed by PubChem (NCBI)