Necrosulfonamide
cas: 432531-71-0 — see every product listed under this CAS number, including other names
Necrosulfonamide (CAS 432531-71-0) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 10mg, 1mg. Offered by: TRC.
| brand | TRC |
|---|---|
| catalog number | TRC-N388600-100MG |
| cas | 432531-71-0 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 100mg | price on request | |
| TRC | 10mg | price on request | |
| TRC | 1mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Necrosulfonamide is a sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway. It has a role as a necroptosis inhibitor and a neuroprotective agent. It is a member of thiophenes, a sulfonamide and a member of pyrazines.
Source: ChEBI
| Molecular formula | C18H15N5O6S2 |
|---|---|
| Molecular weight | 461.5 g/mol |
| IUPAC name | (E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide |
| InChIKey | FNPPHVLYVGMZMZ-XBXARRHUSA-N |
| SMILES | COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)/C=C/C3=CC=C(S3)[N+](=O)[O-] |
Computed by PubChem (NCBI)