PCI–24781 (CRA–024781)
cas: 783355-60-2 — see every product listed under this CAS number, including other names
PCI–24781 (CRA–024781) (CAS 783355-60-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 200mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14682-10 |
| cas | 783355-60-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 891.91 Pln | |
| GLPBio | 200mg | 4336.76 Pln | |
| GLPBio | 5mg | 746.82 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 774.90 Pln | |
| GLPBio | 50mg | 1767.16 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Abexinostat is a 1-benzofuran substituted by {2-[4-(hydroxycarbamoyl)phenoxy]ethyl}aminocarbonyl and (dimethylamino)methyl groups at positions 2 and 3, respectively. It is a potent pan-HDAC inhibitor whose major target is HDAC1 (Ki = 7 nM). It has a role as a radiosensitizing agent, an autophagy inducer, an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a secondary carboxamide, a hydroxamic acid, an aromatic ether, a member of 1-benzofurans and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C21H23N3O5 |
|---|---|
| Molecular weight | 397.4 g/mol |
| IUPAC name | 3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide |
| InChIKey | MAUCONCHVWBMHK-UHFFFAOYSA-N |
| SMILES | CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO |
Computed by PubChem (NCBI)