Products 1632250-49-7

CAS 1632250-49-7 appears in our catalog under these names: PF-06446846/ 99.4% (existing batch purity), PF–06446846, N-(3-Chloropyridin-2-yl)-N-((3R)-piperidin-3-yl)-4-(triazolo(4,5-b)pyridin-3-yl)benzamide, (R)-4-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide, PF-06446846. Offered by: TargetMol, GLPBio, Biosynth, Chemat, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, Get quote.

PF-06446846/ 99.4% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 784.16
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PF–06446846
GLPBio
  • size: 25mg, 5mg
  • Variants: 2
from 1486.33
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N-(3-Chloropyridin-2-yl)-N-((3R)-piperidin-3-yl)-4-(triazolo(4,5-b)pyridin-3-yl)benzamide
Biosynth
  • size: 10mg, 5mg, 25mg, 50mg
  • Variants: 4
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(R)-4-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-N-(3-chloropyridin-2-yl)-N-(piperidin-3-yl)benzamide
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 381.20
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PF-06446846
MedChemExpress
  • size: Get quote
  • Variants: 1
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Structural formula: {0} (CAS {1})

PF-06446846 is a triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9. It has a role as an EC 3.4.21.61 (kexin) inhibitor and an antilipemic drug. It is a tertiary carboxamide, a member of benzamides, a member of piperidines, a monochloropyridine and a triazolopyridine.

Source: ChEBI

Identity
Molecular formulaC22H20ClN7O
Molecular weight433.9 g/mol
IUPAC nameN-(3-chloro-2-pyridinyl)-N-[(3R)-piperidin-3-yl]-4-(triazolo[4,5-b]pyridin-3-yl)benzamide
InChIKeyFDTXHWQFIXYHCL-QGZVFWFLSA-N
SMILESC1C[C@H](CNC1)N(C2=C(C=CC=N2)Cl)C(=O)C3=CC=C(C=C3)N4C5=C(C=CC=N5)N=N4

Computed by PubChem (NCBI)

Synonyms: MVM, C22H20ClN7O, orb1219809, orb1298749