cas: 1290543-63-3 — see every product listed under this CAS number, including other names
PF-3084014, 99+%, 99+% (CAS 1290543-63-3) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 100mg, 250mg, 1g. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch110CE5-50mg |
| cas | 1290543-63-3 |
| size | 50mg |
| availability | 5g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 50mg | 515.60 Pln | |
| Chemat | 100mg | 827.60 Pln | |
| Chemat | 250mg | 1518.80 Pln | |
| Chemat | 1g | 4000.40 Pln |
| purity | 99+% |
|---|---|
| delivery time | 3 weeks |
Nirogacestat is a member of the class of imidazoles that is 1H-imidazole substituted by a 1-[(2,2-dimethylpropyl)amino]-2-methylpropan-2-yl group at position 1 and a {N-[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-L-norvalyl}amino group at position 4. It is a gamma-secretase inhibitor whose hydrobromide salt is indicated for adult patients with progressing desmoid tumours who require systemic treatment. It has a role as an antineoplastic agent and a gamma-secretase modulator. It is a secondary carboxamide, a member of imidazoles, a member of tetralins, an organofluorine compound and a secondary amino compound. It is a conjugate base of a nirogacestat(2+).
Source: ChEBI
| Molecular formula | C27H41F2N5O |
|---|---|
| Molecular weight | 489.6 g/mol |
| IUPAC name | (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide |
| InChIKey | VFCRKLWBYMDAED-REWPJTCUSA-N |
| SMILES | CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=C(C2)C(=CC(=C3)F)F |
Computed by PubChem (NCBI)