PF-3758309

cas: 898044-15-0 — see every product listed under this CAS number, including other names

PF-3758309 (CAS 898044-15-0) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 250mg, 100mg. Offered by: Biosynth.

brandBiosynth
catalog numberYKB04415-50mg
cas898044-15-0
size50mg
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Available pack sizes

brand size price
Biosynth 50mg price on request
Biosynth 250mg price on request
Biosynth 100mg price on request

properties

categoryLife Sciences
sub-category 1Ligands
purityNo data
delivery time3-4 Weeks
Structural formula: {0} (CAS {1})

PF-3758309 is a member of the class of thienopyrimidines that is thieno[3,2-d]pyrimidine substituted by methyl and (5-{[(1S)-2-(dimethylamino)-1-phenylethyl]carbamoyl}-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)amino groups at positions 2 and 4, respectively. It is a potent inhibitor of PAK4 and inhibits the growth of multiple human tumor xenografts. It has a role as an antineoplastic agent, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an apoptosis inducer. It is a thienopyrimidine, a member of benzenes, a pyrrolopyrazole, a member of ureas, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC25H30N8OS
Molecular weight490.6 g/mol
IUPAC nameN-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-d]pyrazole-5-carboxamide
InChIKeyAYCPARAPKDAOEN-LJQANCHMSA-N
SMILESCC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[C@H](CN(C)C)C5=CC=CC=C5)SC=C2

Computed by PubChem (NCBI)

Synonyms: example 114 [US8530652], compound 1 [PMID: 24432870], example 114 (US8530652), compound 1 (PMID: 24432870), 898044-15-0 (free base), orb1221674, orb1300605

Also listed as

PF-3758309/ 99.37% (existing batch purity) TargetMol CAS 898044-15-0
PF–3758309 GLPBio CAS 898044-15-0
PF-3758309, 99.79% MedChemExpress CAS 898044-15-0
(S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno[3,2-d]pyrimidin-4-yl)amino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide, 98+% BLDpharm CAS 898044-15-0
N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide, 98+% Chemat CAS 898044-15-0