Products 898044-15-0
CAS 898044-15-0 appears in our catalog under these names: PF-3758309/ 99.37% (existing batch purity), PF–3758309, PF-3758309, PF-3758309 98+%, N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide, 98+%, 98+%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso), 250mg, 10mM/1mL.
PF-3758309 is a member of the class of thienopyrimidines that is thieno[3,2-d]pyrimidine substituted by methyl and (5-{[(1S)-2-(dimethylamino)-1-phenylethyl]carbamoyl}-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)amino groups at positions 2 and 4, respectively. It is a potent inhibitor of PAK4 and inhibits the growth of multiple human tumor xenografts. It has a role as an antineoplastic agent, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor and an apoptosis inducer. It is a thienopyrimidine, a member of benzenes, a pyrrolopyrazole, a member of ureas, a secondary amino compound and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C25H30N8OS |
|---|---|
| Molecular weight | 490.6 g/mol |
| IUPAC name | N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-d]pyrazole-5-carboxamide |
| InChIKey | AYCPARAPKDAOEN-LJQANCHMSA-N |
| SMILES | CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[C@H](CN(C)C)C5=CC=CC=C5)SC=C2 |
Computed by PubChem (NCBI)