PLX 4720

cas: 918505-84-7 — see every product listed under this CAS number, including other names

PLX 4720 (CAS 918505-84-7) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 10mg, 50mg, 100mg, 250mg. Offered by: Biosynth.

brandBiosynth
catalog numberFC34125-25mg
cas918505-84-7
size25mg
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Available pack sizes

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properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks

PLX-4720 is a pyrrolopyridine that is vemurafenib in which the p-chlorophenyl group has been replaced by chlorine. It is a potent and selective inhibitor of the Raf kinase B-Raf(V600E). It has a role as an antineoplastic agent and a B-Raf inhibitor. It is a sulfonamide, an organochlorine compound, a difluorobenzene, a pyrrolopyridine and an aromatic ketone.

Source: ChEBI

Identity
Molecular formulaC17H14ClF2N3O3S
Molecular weight413.8 g/mol
IUPAC nameN-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
InChIKeyYZDJQTHVDDOVHR-UHFFFAOYSA-N
SMILESCCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)Cl)F

Computed by PubChem (NCBI)

Synonyms: N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide, C17H14ClF2N3O3S, 3c4c, orb1223650, orb1305431

Also listed as

PLX–4720 GLPBio CAS 918505-84-7
PLX-4720/ 99.83% (existing batch purity) TargetMol CAS 918505-84-7
PLX4720 Chemat CAS 918505-84-7
n-[3-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide, 99+%, 99+% Chemat CAS 918505-84-7
PLX-4720, 99.90% MedChemExpress CAS 918505-84-7
PLX-4720 (Standard) MedChemExpress CAS 918505-84-7