Products 1303420-67-8

CAS 1303420-67-8 appears in our catalog under these names: PLX5622/ 99.41% (existing batch purity), PLX5622, PLX5622 98%, 6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine, 98%, 98%, PLX5622, 99.95%. Offered by: TargetMol, Biosynth, Ambeed, Chemat, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 5g, 1mg.

PLX5622/ 99.41% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 810.99
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PLX5622
Biosynth
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
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PLX5622 98%
Ambeed
  • size: 5g, 1mg, 5mg, 10mg
  • Variants: 9
from 186.81
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6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 131.60
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PLX5622, 99.95%
MedChemExpress
  • size: 10mM/1mL, 50 mg, 5 mg, 25 mg
  • Variants: 7
from 361.49
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PLX5622 in AIN-76A Diet (1200 ppm)
MedChemExpress
  • size: 250 g (300 mg PLX5622 in diet)
  • Variants: 1
from 5637.07
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6-Fluoro-N-((5-fluoro-2-methoxypyridin-3-yl)methyl)-5-((5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine, 98%
Fluorochem
  • size: 250mg
  • Variants: 1
from 5797.98
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Structural formula: {0} (CAS {1})

PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor. PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is mostly used in the way of feed free diet.

Source: ChEBI

Identity
Molecular formulaC21H19F2N5O
Molecular weight395.4 g/mol
IUPAC name6-fluoro-N-[(5-fluoro-2-methoxy-3-pyridinyl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine
InChIKeyNSMOZFXKTHCPTQ-UHFFFAOYSA-N
SMILESCC1=CC2=C(NC=C2CC3=C(N=C(C=C3)NCC4=C(N=CC(=C4)F)OC)F)N=C1

Computed by PubChem (NCBI)

Synonyms: orb1220643, orb1300073, s8874