Products 571190-30-2

CAS 571190-30-2 appears in our catalog under these names: PD-0332991, 97%, Palbociclib, Palbociclib, >95% (HPLC), Palbociclib/ 99.76% (existing batch purity), PD 0332991 (Palbociclib). Offered by: Combi-blocks, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 1g, 25g, 5g, 10g, on request, 100mg, 250mg, 50mg.

PD-0332991, 97%
Combi-blocks
  • size: 1g, 25g, 5g, 10g
  • Variants: 4
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Palbociclib
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 2g, 1g
  • Variants: 7
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Palbociclib, >95% (HPLC)
TRC
  • size: 100mg, 250mg, 50mg
  • Variants: 3
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Palbociclib/ 99.76% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 50mg, 100mg
  • Variants: 4
from 499.07
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PD 0332991 (Palbociclib)
GLPBio
  • size: 10mg, 100mg, 5mg, 50mg
  • Variants: 5
from 597.04
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Palbociclib - Bio-X â„¢
Biosynth
  • size: 1mg
  • Variants: 1
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Palbociclib, >97.0%(HPLC)(T)
TCI
  • size: 200mg, 1g
  • Variants: 2
from 339.62
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Palbociclib, 98.00%
Chemat
  • size: 25mg, 5mg
  • Variants: 2
from 674.11
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Palbociclib 99%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 6
from 197.94
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Palbociclib, 99.97%
MedChemExpress
  • size: 1 g, 500 mg, 100 mg, 10 mg
  • Variants: 7
from 407.93
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Palbociclib (Standard), 99.23%
MedChemExpress
  • size: 10 mg, 50 mg, 100 mg, 5 mg
  • Variants: 5
from 695.86
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Structural formula: {0} (CAS {1})

Palbociclib is a member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of cyclopentanes, a member of piperidines, an aminopyridine, a pyridopyrimidine, a secondary amino compound, a tertiary amino compound and an aromatic ketone.

Source: ChEBI

Identity
Molecular formulaC24H29N7O2
Molecular weight447.5 g/mol
IUPAC name6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrido[2,3-d]pyrimidin-7-one
InChIKeyAHJRHEGDXFFMBM-UHFFFAOYSA-N
SMILESCC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C

Computed by PubChem (NCBI)

Synonyms: Palbociclib, Ibrance, palbociclibum, Palbociclib(PD0332991), LQQ, Palbociclib free base, 2euf, Palbociclib [USAN], 571190-30-2 (free base), Palbociclib [USAN:INN]