Pemetrexed disodium

cas: 150399-23-8 — see every product listed under this CAS number, including other names

Pemetrexed disodium (CAS 150399-23-8) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 500mg, 1000mg, 2000mg. Offered by: Biosynth.

brandBiosynth
catalog numberFP26784-250mg
cas150399-23-8
size250mg
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Available pack sizes

brand size price
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Biosynth 2000mg price on request

properties

categoryResearch Chemicals
purityNo data
delivery time1-2 weeks

Pemetrexed disodium is an organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It contains a pemetrexed(2-).

Source: ChEBI

Identity
Molecular formulaC20H19N5Na2O6
Molecular weight471.4 g/mol
IUPAC namedisodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
InChIKeyNYDXNILOWQXUOF-GXKRWWSZSA-L
SMILESC1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]

Computed by PubChem (NCBI)

Synonyms: Pemetrexed disodium, Pemetrexed sodium salt, Almita, Disodium, Pemetrexed, Alimta, Rolazar, Tifolar, Pemetrexed disodium [USAN], Pemetrexed disodium (USAN), orb1226173
Related forms of this compound
disodium;(2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate C20H19N5Na2O6

Also listed as

Pemetrexed Disodium Salt Chemat Brand CAS 150399-23-8
Pemetrexed disodium/ 99.92% (existing batch purity) TargetMol CAS 150399-23-8
Pemetrexed GLPBio CAS 150399-23-8
Pemetrexed disodium salt - Bio-X â„¢ Biosynth CAS 150399-23-8
Pemetrexed disodium 99% Ambeed CAS 150399-23-8
Sodium (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate, 99%, 99% Chemat CAS 150399-23-8
Pemetrexed (disodium), 99.99% MedChemExpress CAS 150399-23-8