CAS 150399-23-8 appears in our catalog under these names: Pemetrexed Disodium Salt, Pemetrexed disodium/ 99.92% (existing batch purity), Pemetrexed, Pemetrexed disodium, Pemetrexed disodium salt - Bio-X â„¢. Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: on request, 1g, 25mg, 50mg, 100mg, 200mg, 500mg, 2g.
Pemetrexed disodium is an organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It contains a pemetrexed(2-).
Source: ChEBI
| Molecular formula | C20H19N5Na2O6 |
|---|---|
| Molecular weight | 471.4 g/mol |
| IUPAC name | disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate |
| InChIKey | NYDXNILOWQXUOF-GXKRWWSZSA-L |
| SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] |
Computed by PubChem (NCBI)