cas: 1092364-38-9 — see every product listed under this CAS number, including other names
Poziotinib, >95% (HPLC) (CAS 1092364-38-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 1mg, 5mg. Offered by: TRC.
| brand | TRC |
|---|---|
| catalog number | TRC-P215770-10MG |
| cas | 1092364-38-9 |
| size | 10mg |
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| brand | size | price | |
|---|---|---|---|
| TRC | 10mg | price on request | |
| TRC | 1mg | price on request | |
| TRC | 5mg | price on request |
| purity | >95% (HPLC) |
|---|---|
| delivery time | To be confirmed by Chemat |
Poziotinib is a member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations. It has a role as an antineoplastic agent, an apoptosis inducer and an epidermal growth factor receptor antagonist. It is a member of acrylamides, a dichlorobenzene, an aromatic ether, a member of quinazolines, a diether, a N-acylpiperidine, a substituted aniline, a secondary amino compound and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H21Cl2FN4O3 |
|---|---|
| Molecular weight | 491.3 g/mol |
| IUPAC name | 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one |
| InChIKey | LPFWVDIFUFFKJU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C |
Computed by PubChem (NCBI)