Pralatrexate, 99.23%
cas: 146464-95-1 — see every product listed under this CAS number, including other names
Pralatrexate, 99.23% (CAS 146464-95-1) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 10 mg, 25 mg, 100 mg, 5 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-10446-10mM/1mL |
| cas | 146464-95-1 |
| size | 10mM/1mL |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 561.18 Pln | |
| MedChemExpress | 10 mg | 719.08 Pln | |
| MedChemExpress | 25 mg | 1081.31 Pln | |
| MedChemExpress | 100 mg | 2233.02 Pln | |
| MedChemExpress | 5 mg | 542.60 Pln | |
| MedChemExpress | 50 mg | 1438.90 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.23% |
Pralatrexate is a pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. It has a role as an antimetabolite, an antineoplastic agent and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a N-acyl-L-glutamic acid, a member of pteridines and a terminal acetylenic compound.
Source: ChEBI
| Molecular formula | C23H23N7O5 |
|---|---|
| Molecular weight | 477.5 g/mol |
| IUPAC name | (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid |
| InChIKey | OGSBUKJUDHAQEA-WMCAAGNKSA-N |
| SMILES | C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Computed by PubChem (NCBI)
Synonyms:
Pralatrexate, Folotyn, 10-Propargyl-10-deazaaminopterin, pralatrexato, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid, pralatrexatum, N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid, L-Glutamic acid, N-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-, N-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid, N-(4-(1-((2,4-Diaminopteridin-6-yl)methyl)but-3-yn-1-yl)benzoyl)-L-glutamic Acid