Products 263717-53-9
CAS 263717-53-9 appears in our catalog under these names: PPT, Propyl pyrazole triol/ 98.39% (existing batch purity), Propyl pyrazole triol, 99%, 99%, Propyl pyrazole triol, 99.11%, Propyl pyrazole triol (Standard). Offered by: TRC, GLPBio, TargetMol, Biosynth, Chemat. Available pack sizes: 500mg, 1mg, 10mg, 25mg, 5mg, 50mg, 100mg, 250mg.
4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol is a pyrazole that is 1H-pyrazole bearing three 4-hydroxyphenyl substituents at positions 1, 3 and 5 as well as a propyl substituent at position 4. Potent, subtype-selective estrogen receptor agonist (EC50 ~ 200 pM); displays 410-fold selectivity for ERalpha over ERbeta. Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo. It has a role as an estrogen receptor agonist. It is a member of pyrazoles and a member of phenols.
Source: ChEBI
| Molecular formula | C24H22N2O3 |
|---|---|
| Molecular weight | 386.4 g/mol |
| IUPAC name | 4-[1,3-bis(4-hydroxyphenyl)-4-propylpyrazol-5-yl]phenol |
| InChIKey | IOTXSIGGFRQYKW-UHFFFAOYSA-N |
| SMILES | CCCC1=C(N(N=C1C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O |
Computed by PubChem (NCBI)
Synonyms:
propyl pyrazole triol, PROPYLPYRAZOLETRIOL, PPT, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)triphenol, 1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole, Phenol, 4,4',4''-(4-propyl-1H-pyrazole-1,3,5-triyl)tris-, 4,4',4''-(4-propyl-(1H)-pyrazole-1,3,5-triyl)trisphenol, 1,3,5-tris(4-hydroxyphenyl)-4-propylpyrazole, 4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol, 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol