QNZ (EVP4593)

cas: 545380-34-5 — see every product listed under this CAS number, including other names

QNZ (EVP4593) (CAS 545380-34-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 25mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGC11751-5
cas545380-34-5
size5mg
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Available pack sizes

brand size price
GLPBio 5mg 648.53 Pln
GLPBio 25mg 1350.60 Pln
GLPBio 10mM (in 1ml dmso) 667.25 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

EVP4593 is a member of the class of quinazolines that is quinazoline substituted by [2-(4-phenoxyphenyl)ethyl]amino and amino groups at positions 4 and 6, respectively. It is an inhibitor of NF-B signal transduction pathway and exhibits protective effects in oncology, cardiovascular disease and parasite invasion. It has a role as an antiparasitic agent, an antineoplastic agent, an EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor, an anti-inflammatory agent, an apoptosis inducer and a NF-kappaB inhibitor. It is a member of benzenes, an aromatic ether, a member of quinazolines, a primary amino compound and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC22H20N4O
Molecular weight356.4 g/mol
IUPAC name4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine
InChIKeyIBAKVEUZKHOWNG-UHFFFAOYSA-N
SMILESC1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N

Computed by PubChem (NCBI)

Synonyms: QNZ quinazolinediamine, 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline, QNZ, N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine, 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, NF-kB activation inhibitor, Curator_000005, N4-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, 4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]-, N~4~-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine
Isomers (same molecular formula)
2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-N,N-dimethylacetamide C22H20N4O
(E)-N-ethoxy-1-[1-(3-pyridin-3-ylphenyl)benzimidazol-5-yl]ethanimine C22H20N4O
4-[2-amino-5-(4-cyanophenyl)-3-pyridinyl]-N-propan-2-ylbenzamide C22H20N4O

Also listed as

6-Amino-4-(4-phenoxyphenylethylamino)quinazoline TRC CAS 545380-34-5
QNZ/ 99.86% (existing batch purity) TargetMol CAS 545380-34-5
QNZ, 98% Thermo Scientific (Alfa Aesar) CAS 545380-34-5
QNZ, >98.0%(HPLC) TCI CAS 545380-34-5
EVP4593 Biosynth CAS 545380-34-5
QNZ 99% Ambeed CAS 545380-34-5
NF-╬║B Activation Inhibitor 1PC X 1MG Sigma-Aldrich CAS 545380-34-5
N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine, 99%, 99% Chemat CAS 545380-34-5
QNZ, 99.50% MedChemExpress CAS 545380-34-5
QNZ (Standard) MedChemExpress CAS 545380-34-5
N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine, 99% Fluorochem CAS 545380-34-5