cas: 6151-30-0 — see every product listed under this CAS number, including other names
Quinacrine Dihydrochloride Dihydrate (CAS 6151-30-0) is a chemical reagent available from Chemat. Available pack sizes: 25mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC25811-25 |
| cas | 6151-30-0 |
| size | 25mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 25mg | 676.61 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Quinacrine dihydrochloride dihydrate is quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53.
Source: ChEBI
| Molecular formula | C23H36Cl3N3O3 |
|---|---|
| Molecular weight | 508.9 g/mol |
| IUPAC name | 4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine;dihydrate;dihydrochloride |
| InChIKey | RZFNKJVCPDLQQA-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.O.O.Cl.Cl |
Computed by PubChem (NCBI)