CAS 6151-30-0 appears in our catalog under these names: Quinacrine HCl, 98%, Quinacrine (hydrochloride hydrate), Quinacrine Dihydrochloride Dihydrate, Quinacrine (hydrochloride hydrate) (Standard), Quinacrine (hydrochloride hydrate), 98.18%. Offered by: AmBeed, GLPBio, MedChemExpress. Available pack sizes: 25mg, 100mg, 1g, 500mg, 5g, Get quote, 100 mg.
Quinacrine dihydrochloride dihydrate is quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53.
Source: ChEBI
| Molecular formula | C23H36Cl3N3O3 |
|---|---|
| Molecular weight | 508.9 g/mol |
| IUPAC name | 4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine;dihydrate;dihydrochloride |
| InChIKey | RZFNKJVCPDLQQA-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.O.O.Cl.Cl |
Computed by PubChem (NCBI)