RSL3
cas: 1219810-16-8 — see every product listed under this CAS number, including other names
RSL3 (CAS 1219810-16-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 2mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC12431-10 |
| cas | 1219810-16-8 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1139.98 Pln | |
| GLPBio | 2mg | 901.27 Pln | |
| GLPBio | 25mg | 2024.59 Pln | |
| GLPBio | 5mg | 826.38 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1022.97 Pln | |
| GLPBio | 50mg | 3119.83 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
RSL3 is a beta-carboline that is 2,3,4,4a,9,9a-hexahydro-1H-beta-carboline in which the hydrogens at positions 1, 2 and 3 are replaced by 4-(methoxycarbonyl)phenyl, chloroacetyl and methoxycarbonyl groups, respectively (the 1S,2R stereoisomer). It is a potential antineoplastic agent which triggers ferroptosis by inactivating the glutathione peroxidase 4 (GPX4) enzyme. It has a role as a ferroptosis inducer, an EC 1.11.1.9 (glutathione peroxidase) inhibitor and an antineoplastic agent. It is a tertiary carboxamide, a methyl ester, a benzoate ester, an organochlorine compound, a diester and a member of beta-carbolines.
Source: ChEBI
| Molecular formula | C23H23ClN2O5 |
|---|---|
| Molecular weight | 442.9 g/mol |
| IUPAC name | methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,4a,9,9a-hexahydropyrido[3,4-b]indole-3-carboxylate |
| InChIKey | CKRZDIUOUCGSBK-YBKKDXPLSA-N |
| SMILES | COC(=O)[C@H]1CC2C([C@@H](N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24 |
Computed by PubChem (NCBI)
Synonyms:
ras-selective lethal small molecule 3