Products 865838-26-2
CAS 865838-26-2 appears in our catalog under these names: 4-Amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2(1H)-pyrimidinone, 97.46% ,, 97.46% ,, RX-3117/ 99.55% (existing batch purity), RX-3117, 99.25%. Offered by: Chemat, TargetMol, MedChemExpress. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 1 mg.
Roducitabine is a triol that is (1S,2R)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol which is substituted by a 4-amino-2-oxopyrimidin-1(2H)-yl group at position 5. It is a cytidine analog which exhibits anticancer activity in several cancers, including gemcitabine-resistant tumours. It has a role as an antimetabolite, an antineoplastic agent, a prodrug, a DNA synthesis inhibitor and an apoptosis inducer. It is a primary allylic alcohol, a triol and an organofluorine compound.
Source: ChEBI
| Molecular formula | C10H12FN3O4 |
|---|---|
| Molecular weight | 257.22 g/mol |
| IUPAC name | 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidin-2-one |
| InChIKey | QLLGKCJUPWYJON-HLTSFMKQSA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H](C(=C2F)CO)O)O |
Computed by PubChem (NCBI)
Synonyms:
Roducitabine, fluorocyclopentenylcytosine, Roducitabine [USAN], RODUCITABINE [INN], fluorocyclopentenyl cytosine, fluorocyclopentenyl-cytosine, Roducitabine (USAN), 1-[(1S,4R,5S)-2-Fluoro-3-(hydroxymethyl)-4,5-dihydroxy-2-cyclopentenyl]cytosine, 1-((1S,4R,5S)-2-fluoro-3-(hydroxymethyl)-4,5-dihydroxy-2-cyclopentenyl)cytosine, Cytidine Analog RX-3117