Ravuconazole

cas: 182760-06-1 — see every product listed under this CAS number, including other names

Ravuconazole (CAS 182760-06-1) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 1mg. Offered by: Chemat Brand, TRC.

brandChemat Brand
catalog numberULR150001
cas182760-06-1
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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purityNo data
categoryChemicals
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Structural formula: {0} (CAS {1})

Ravuconazole is a member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14alpha demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4). It has a role as an EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor, an antileishmanial agent, an ergosterol biosynthesis inhibitor and an antifungal drug. It is a nitrile, a tertiary alcohol, a member of fluorobenzenes, a member of triazoles and a member of 1,3-thiazoles.

Source: ChEBI

Identity
Molecular formulaC22H17F2N5OS
Molecular weight437.5 g/mol
IUPAC name4-[2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
InChIKeyOPAHEYNNJWPQPX-RCDICMHDSA-N
SMILESC[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=NC=N3)(C4=C(C=C(C=C4)F)F)O

Computed by PubChem (NCBI)

Synonyms: Ravuconazole, Ravuconazole [INN], ravuconazol, ravuconazolum, RCZ, Ravuconazole (Standard), Ravuconazole (prop.INN), RAVUCONAZOLE [MI], RAVUCONAZOLE [MART.], RAVUCONAZOLE [WHO-DD]
Related forms of this compound
2,3,5,6-tetradeuterio-4-[2-[(2R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
Isomers (same molecular formula)
4-[2-[(2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3S)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
2,3,5,6-tetradeuterio-4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS

Also listed as

Ravuconazole (BMS–207147) GLPBio CAS 182760-06-1
Ravuconazole/ 99.86% (existing batch purity) TargetMol CAS 182760-06-1
Ravuconazole, >98.0%(HPLC)(qNMR) TCI CAS 182760-06-1
Ravuconazole 98% Ambeed CAS 182760-06-1
Ravuconazole, 98%, 98% Chemat CAS 182760-06-1
Ravuconazole, 99.91% MedChemExpress CAS 182760-06-1
Ravuconazole (Standard) MedChemExpress CAS 182760-06-1
RAVUCONAZOLE, 98% Fluorochem CAS 182760-06-1