Products 182760-06-1

CAS 182760-06-1 appears in our catalog under these names: Ravuconazole (BMS–207147), Ravuconazole, Ravuconazole/ 99.86% (existing batch purity), Ravuconazole, >98.0%(HPLC)(qNMR), Ravuconazole 98%. Offered by: GLPBio, Chemat Brand, TRC, TargetMol, TCI. Available pack sizes: 1mg, on request, 10mg, 2mg, 5mg, 25mg, 50mg, 100mg.

Ravuconazole (BMS–207147)
GLPBio
  • size: 1mg, 10mg, 10mM (in 1ml dmso), 25mg
  • Variants: 6
from 629.80
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Ravuconazole
Chemat Brand, TRC
  • size: on request, 10mg, 1mg
  • Variants: 3
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Ravuconazole/ 99.86% (existing batch purity)
TargetMol
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 6
from 392.86
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Ravuconazole, >98.0%(HPLC)(qNMR)
TCI
  • size: 200mg, 1g
  • Variants: 2
from 596.81
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Ravuconazole 98%
Ambeed
  • size: 10g, 250mg, 1g, 5g
  • Variants: 4
from 470.50
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Ravuconazole, 98%, 98%
Chemat
  • size: 250mg, 1g, 5g, 10g
  • Variants: 5
from 198.80
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Ravuconazole, 99.91%
MedChemExpress
  • size: 50 mg, 100 mg, 5 mg, 25 mg
  • Variants: 6
from 407.93
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Ravuconazole (Standard)
MedChemExpress
  • size: 5 mg, 100 mg, 10 mg, 25 mg
  • Variants: 5
from 1243.85
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RAVUCONAZOLE, 98%
Fluorochem
  • size: 250mg, 1g, 5g
  • Variants: 3
from 320.74
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Structural formula: {0} (CAS {1})

Ravuconazole is a member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14alpha demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4). It has a role as an EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor, an antileishmanial agent, an ergosterol biosynthesis inhibitor and an antifungal drug. It is a nitrile, a tertiary alcohol, a member of fluorobenzenes, a member of triazoles and a member of 1,3-thiazoles.

Source: ChEBI

Identity
Molecular formulaC22H17F2N5OS
Molecular weight437.5 g/mol
IUPAC name4-[2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
InChIKeyOPAHEYNNJWPQPX-RCDICMHDSA-N
SMILESC[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=NC=N3)(C4=C(C=C(C=C4)F)F)O

Computed by PubChem (NCBI)

Synonyms: Ravuconazole, Ravuconazole [INN], ravuconazol, ravuconazolum, RCZ, Ravuconazole (Standard), Ravuconazole (prop.INN), RAVUCONAZOLE [MI], RAVUCONAZOLE [MART.], RAVUCONAZOLE [WHO-DD]
Related forms of this compound
2,3,5,6-tetradeuterio-4-[2-[(2R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
Isomers (same molecular formula)
4-[2-[(2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3S)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
2,3,5,6-tetradeuterio-4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS
4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile C22H17F2N5OS