Refametinib
cas: 923032-37-5 — see every product listed under this CAS number, including other names
Refametinib (CAS 923032-37-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 100mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC16872-5 |
| cas | 923032-37-5 |
| size | 5mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 5mg | 737.45 Pln | |
| GLPBio | 10mg | 896.59 Pln | |
| GLPBio | 100mg | 2511.36 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 821.70 Pln | |
| GLPBio | 50mg | 1593.99 Pln | |
| Biosynth | 50mg | price on request | |
| Biosynth | 10mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Refametinib is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. Refametinib specifically inhibits mitogen-activated protein kinase kinase 1 (MAP2K1 or MAPK/ERK kinase 1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation.
Source: ChEBI
| Molecular formula | C19H20F3IN2O5S |
|---|---|
| Molecular weight | 572.3 g/mol |
| IUPAC name | N-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)-6-methoxyphenyl]-1-[(2S)-2,3-dihydroxypropyl]cyclopropane-1-sulfonamide |
| InChIKey | RDSACQWTXKSHJT-NSHDSACASA-N |
| SMILES | COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)C[C@@H](CO)O)NC3=C(C=C(C=C3)I)F)F)F |
Computed by PubChem (NCBI)