Products 144092-31-9
CAS 144092-31-9 appears in our catalog under these names: Ro 41-5253/ 98%, Ro 41–5253, Ro 41-5253, 98.00% ,, 98.00% ,, Ro 41-5253, 98.97%. Offered by: TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 1mg, 10mg, 25mg, 5mg, 50 mg, 25 mg, 100 mg, 10 mg.
Ro 41-5253 is a thiochromane that is 3,4-dihydro-2H-1-benzothiopyran S,S-dioxide in which the hydrogens at position 4 are both replaced by methyl groups, the hydrogens at position 7 is replaced by a heptyloxy group, while the hydrogen at position 6 is replaced by a 1-phenylprop-1-en-2-yl group, the phenyl group of which is substituted at the para position by a carboxy group. It is a selective antagonist for retinoic acid receptor alpha. It has a role as an apoptosis inducer and a retinoic acid receptor alpha antagonist. It is a member of benzoic acids, an aromatic ether, a sulfone and a thiochromane.
Source: ChEBI
| Molecular formula | C28H36O5S |
|---|---|
| Molecular weight | 484.6 g/mol |
| IUPAC name | 4-[(E)-2-(7-heptoxy-4,4-dimethyl-1,1-dioxo-2,3-dihydrothiochromen-6-yl)prop-1-enyl]benzoic acid |
| InChIKey | JEIWQRITHXYGIF-LVZFUZTISA-N |
| SMILES | CCCCCCCOC1=CC2=C(C=C1/C(=C/C3=CC=C(C=C3)C(=O)O)/C)C(CCS2(=O)=O)(C)C |
Computed by PubChem (NCBI)